发明名称 NOUVELLES ARALKYLE-1,2-DIAMINES POSSEDANT UNE ACTIVITE CALCIMIMETIQUE ET LEUR MODE DE PREPARATION
摘要 The invention concerns compounds of general formula (I) wherein: X represents a SO2 or CH2 group; R1 represents a hydrogen or halogen atom or an alkoxy, aryl aralkyl group or an alkyl group substituted or not with one or several halogen atoms, n is equal to 0, 1 or 2, and R2 represents a hydrogen or halogen atom or an alkyl or alkoxy group, and their salt with a pharmaceutically acceptable acid. The invention also concerns the method for preparing said compounds, pharmaceutical compositions containing them and their use as modulator of CaSR activity and as medicine particularly designed for treating diseases or physiological disorders involving modulation of CaSR activity.
申请公布号 FR2800735(A1) 申请公布日期 2001.05.11
申请号 FR19990014050 申请日期 1999.11.09
申请人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 发明人 RUAT MARTIAL;POTIER PIERRE JEAN PAUL;DODD ROBERT;DAUBAN PHILIPPE MARCEL;FAURE HELENE VERONIQUE
分类号 A61P1/04;A61K31/132;A61K31/18;A61P3/00;A61P3/14;A61P5/00;A61P5/22;A61P9/10;A61P13/12;A61P19/10;A61P25/28;A61P35/00;C07C211/27;C07C217/08;C07C311/05;C07C311/16;C07C311/18;C07C311/29;C07C311/38;C07D333/34;C07F7/08;(IPC1-7):C07C311/16;C07C211/30;A61K31/137 主分类号 A61P1/04
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