发明名称 |
IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES |
摘要 |
<p>2-Aminopropane is used as the amine donor in the stereoselective synthesis of a chiral amine from a ketone with a transaminase. In a typical embodiment, (S)-1-methoxy-2-aminopropane is prepared by bringing methoxyacetone into contact with a transaminase in the presence of 2-aminopropane as an amine donor until a substantial amount of methoxyacetone is converted to (S)-1-methoxy-2-aminopropane and 2-aminopropane is converted to acetone. In a second embodiment, L-alanine is prepared by bringing pyruvic acid into contact with a transaminase in the presence of 2-aminopropane as an amine donor.</p> |
申请公布号 |
SK13382000(A3) |
申请公布日期 |
2001.05.10 |
申请号 |
SK20000001338 |
申请日期 |
1999.03.10 |
申请人 |
CELGRO |
发明人 |
WU WEI;BHATIA MOHIT B.;LEWIS CRAIG M.;LANG WEI;WANG ALICE;MATCHAM GEORGE W. |
分类号 |
C12P13/00;C12P13/04;C12P13/06;C12P41/00;(IPC1-7):C12P13/00 |
主分类号 |
C12P13/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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