发明名称 |
NUCLEIC ACID ENCODING PROTEINS INVOLVED IN PROTEIN DEGRADATION, PRODUCTS AND METHODS RELATED THERETO |
摘要 |
In accordance with the present invention, there are provided novel Siah-Mediated-Degradation-Proteins (SMDPs) and/or SCF-Complex Proteins (SCPs). Nucleic acid sequences encoding such proteins and assays employing same are also disclosed. The invention SMDPs and/or SCPs can be employed in a variety of ways, for example, for the production of anti-SMDP and/or SCP antibodies thereto, in therapeutic compositions, and methods employing such proteins and/or antibodies for drug screening, functional genomics and other applications. Also provided are transgenic non-human mammals that express the invention protein.
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申请公布号 |
WO0077207(A3) |
申请公布日期 |
2001.05.10 |
申请号 |
WO2000US15873 |
申请日期 |
2000.06.09 |
申请人 |
THE BURNHAM INSTITUTE;REED, JOHN, C.;MATSUZAWA, SHU-ICHI |
发明人 |
REED, JOHN, C.;MATSUZAWA, SHU-ICHI |
分类号 |
A01K67/027;A61K31/7088;A61K35/76;A61K38/00;A61K39/395;A61K48/00;A61P29/00;A61P35/00;A61P43/00;C07K14/47;C07K16/40;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/64;C12N15/09;C12N15/12;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50;G01N33/53;G01N33/566;G01N33/577;G01N33/58;(IPC1-7):C12N15/12;C12N15/11;C07K16/18;C12N15/00;G01N33/68;A61K38/17;C12N15/62 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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