发明名称 |
Platelet derived growth factor (PDGF) nucleic acid ligand complexes |
摘要 |
This invention discloses a method for preparing a complex comprised of a PDGF Nucleic Acid Ligand and a Non-Immunogenic, High Molecular Weight Compound or Lipophilic Compound by identifying a PDGF Nucleic Acid Ligand by SELEX methodology and associating the PDGF Nucleic Acid Ligand with a Non-Immunogenic, High Molecular Weight Compound or Lipophilic Compound. The invention further discloses Complexes comprising one or more PDGF Nucleic Acid Ligands in association with a Non-Immunogenic, High Molecular Weight Compound or Lipophilic Compound. The invention further includes a Lipid construct comprising a PDGF Nucleic Acid Ligand or Complex and methods for making the same.
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申请公布号 |
US6229002(B1) |
申请公布日期 |
2001.05.08 |
申请号 |
US19970991743 |
申请日期 |
1997.12.16 |
申请人 |
NEXSTAR PHARMACEUTICLAS, INC. |
发明人 |
JANJIC NEBOJSA;GOLD LARRY |
分类号 |
C12Q1/68;A61K31/7088;A61K38/00;A61K47/48;A61K48/00;A61K49/00;A61P9/00;A61P13/12;A61P35/00;C07H21/02;C07H21/04;C07K14/49;C07K14/495;C07K14/50;C07K14/52;C12N15/113;C12N15/115;C12P19/34;(IPC1-7):C07H21/02 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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