Novel succinic acid metallo-beta-lactamase inhibitors and their use in treating bacterial infections

摘要

This invention relates to novel substituted succinic acid metallo- beta -lactamase inhibitors which are useful potentiators of beta -lactam antibiotics. Accordingly, the present invention provides a method of treating bacterial infections in animals or humans which comprises administering, together with a beta -lactam antibiotic, a therapeutically effective amount of a compound of formula (I) including pharmaceutically acceptable salts, prodrugs, anhydrides, and solvates thereof.