| 摘要 |
Improved sealing for microstructures in microfluidic devices (100, 150) havi ng a plurality of units (152) is provided by providing collars (104, 204) surrounding the openings (206) to the microstructures, such as reservoirs (208). The collars (104, 204) are protrusions extending from the surface (10 8, 202) of the devices (100, 150) and the internal walls (210) of the collars (104, 204) generally aligned with the internal walls (210) of the microstructure. Conformable and/or adhesive lids (218, 220) are employed for sealing the microstructures.
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