发明名称 |
METHODS AND COMPOSITIONS FOR TARGETING A CELL |
摘要 |
Oligomeric ligands, such as cysteine knot growth factors, can be displayed o n the surface of viral particles as recombinant fusion proteins. The recombina nt fusion proteins can be used to screen for drugs which will inhibit binding o f an oligomeric ligand to its receptor and for targeting transferable labels, including therapeutic gene products, to cells bearing a receptor specific fo r the oligomeric ligand.
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申请公布号 |
CA2386824(A1) |
申请公布日期 |
2001.04.19 |
申请号 |
CA20002386824 |
申请日期 |
2000.10.09 |
申请人 |
BIOFOCUS DISCOVERY LIMITED |
发明人 |
RUSSELL, STEPHEN JAMES;BELCHER, CRAIG;CHADWICK, MARK PHILIP;GLENN, DAPHNE;BULLOUGH, FRANCES JOANNE |
分类号 |
G01N33/50;A61K48/00;C07K14/15;C07K14/16;C07K14/49;C07K14/52;C07K19/00;C12N7/01;C12N15/09;C12N15/12;C12N15/867;C12Q1/02;G01N33/15;G01N33/53;G01N33/566;(IPC1-7):C12N15/62;C12N15/10;C07K14/475;G01N33/68;C12Q1/70;C12N15/86 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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