发明名称 |
A METHOD FOR PREDICTING THE NEED FOR DOSE REDUCTIONS IN CHEMOTHERAPY FOR PATIENTS WITH BREAST CANCER: A POTENTIAL DECISION AID FOR THE USE OF MYELOID GROWTH FACTORS |
摘要 |
The invention provides provided a method and instrument for predicting the probability of a patient requiring a significant dose reduction in adjuvant chemotherapy for breast cancer and/or predicting whether early treatment with a myeloid growth factor is warranted, by determining the patient's dose-adjusted nadir absolute neutrophil count (ANC) in the first cycle of the chemotherapy schedule, further determining the patient's dose-adjusted percent change in platelet count from day one to the dose-adjusted nadir platelet count in the first cycle of the chemotherapy schedule, and then calculating the probability that the patient will receive a suboptimal chemotherapy dose using the dose-adjusted nadir ANC and dose-adjusted percent change in platelet count.
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申请公布号 |
WO0127618(A2) |
申请公布日期 |
2001.04.19 |
申请号 |
WO2000US41137 |
申请日期 |
2000.10.12 |
申请人 |
NEW ENGLAND MEDICAL CENTER HOSPITAL |
发明人 |
SAVVIDES, PANOS;TERRIN, NORMA;ERBAN, JOHN;SELKER, HARRY, P. |
分类号 |
G01N33/569;G01N33/574;(IPC1-7):G01N33/50 |
主分类号 |
G01N33/569 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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