SYSTEMS AND METHODS FOR CHARACTERIZING A BIOLOGICAL CONDITION OR AGENT USING CALIBRATED GENE EXPRESSION PROFILES

摘要

The invention provides a method, for evaluating a biological condition of a subject, comprising: a. obtaining from the subject a sample having at least one of RNAs and proteins; b. deriving from the sample a first profile data set, the first profile data set including a plurality of members, each membe r being a quantitative measure of the amount of a distinct RNA or protein constituent in a panel of constituents selected so that measurement of the constituents enables measurement of the biological condition; and c. produci ng a calibrated profile data set for the panel, wherein each member of the calibrated profile data set is a function of a corresponding member of the first profile data set and a corresponding member of a baseline profile data set for the panel, the calibrated profile data set providing a measure of th e biological condition of the subject.