| 发明名称 |
FIBROBLAST GROWTH FACTOR-5 (FGF-5) IS A TUMOR ASSOCIATED T-CELL ANTIGEN |
| 摘要 |
Disclosed herein are methods for treating tumors which express or over-express the tumor associated antigen (TAA) fibroblast growth factor 5 (FGF-5), including renal cell carcinoma (RCC) and carcinoma of the prostate and breast. Methods include modulating an immune response, such as increasing an immune response, or modulating FGF-5 expression or activity. The disclosure also includes methods of determining if a subject has an enhanced susceptibility to a disease associated with abnormal FGF-5 expression.
|
| 申请公布号 |
WO0125271(A2) |
申请公布日期 |
2001.04.12 |
| 申请号 |
WO2000US26689 |
申请日期 |
2000.09.29 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;HANADA, KEN-ICHI;YANG, JAMES, C. |
发明人 |
HANADA, KEN-ICHI;YANG, JAMES, C. |
| 分类号 |
C12N15/09;A61K31/7088;A61K35/14;A61K35/76;A61K38/22;A61K39/00;A61K39/39;A61K39/395;A61K45/00;A61K48/00;A61P13/12;A61P35/00;C07K14/50;C07K16/22;C12Q1/02;(IPC1-7):C07K14/00 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
