Nucleotide sequences coding for the eno gene

摘要

An isolated nucleic acid (I) from coryneform bacteria encoding a polypeptide at least 70 % identical with a 425 residue amino acid sequence (S2), or having a complementary nucleotide sequence, or at least 15 consecutive bases of it, is new. An Independent claim is also included for fermentative production of L-amino acids, especially L-lysine, by fermenting a lysine-producing coryneform in which the eno gene has been amplified, and isolating amino acids that have accumulated in the medium or cells.