发明名称 |
N-PHENYL-N'-PHENYLPROPYLPIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF |
摘要 |
<p>N-Phenyl-N'-phenylpropylpiperazine derivatives represented by general formula (1) (wherein R<1> is lower alkyl; R<2> is lower alkoxy; and R<3> is cyano, carboxyl or indolecarbonyl); drugs containing the same; and a process for the preparation thereof. The compounds exhibit potent alpha 1-adrenergic receptor blocking activity and are useful in the prevention and treatment of hypertension, congestive heart failure, myocardial ischemia, arrhythmia, angina pectoris, urinary disturbance and frequent urination due to prostatic hypertrophy, and so on. <CHEM></p> |
申请公布号 |
EP1090913(A1) |
申请公布日期 |
2001.04.11 |
申请号 |
EP19990957637 |
申请日期 |
1999.06.28 |
申请人 |
ZERIA PHARMACEUTICAL CO., LTD. |
发明人 |
SATO, HIROKI;NAGANO, EIICHI;CHIKAZAWA, JUN;TAKEI, MINEO;HIGASHINO, R. |
分类号 |
C07D295/084;C07D295/092;(IPC1-7):C07D209/12;A61K31/495;C07D295/08 |
主分类号 |
C07D295/084 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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