发明名称 Thienodipyridine derivatives, production and use thereof
摘要 A compound of the formula (I):wherein R is hydrogen or C2-6 alkanoyl; X is halogen; and ring A is benzene ring which is optionally substituted by 1 to 4 substituents selected from {circle around (1)} halogen, {circle around (2)} hydroxy, {circle around (3)} C1-6 alkoxy optionally substituted by halogen or phenyl, {circle around (4)} C1-6 alkylthio optionally substituted by halogen or phenyl, {circle around (5)} C1-6 alkyl optionally substituted by halogen, {circle around (6)} C2-6 alkanoylamino or {circle around (7)} carboxy optionally esterified by C1-6 alkyl, or a salt thereof; which can be used for preventing or treating inflammatory disease, arthritis, chronic rheumatoid arthritis, autoimmune diseases, or rejection after organ transplantation.
申请公布号 US6214838(B1) 申请公布日期 2001.04.10
申请号 US19990355218 申请日期 1999.07.23
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 SOHDA TAKASHI;MAKINO HARUHIKO;BABA ATSUO;YAMANE TAIHEI
分类号 A61P29/00;C07D495/14;(IPC1-7):A61K31/436;A61K31/437 主分类号 A61P29/00
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