| 摘要 |
Described is a method for the reduction of aromatic halides of the general formula (I), Ar-Xn (I), wherein Ar represents an aromatic moiety that can be substituted at one or several positions, it may be condensed, or contain at least one heteroatoms selected from the group comprising O, S or N, X represents F, Cl, Br and/or I and n is 1-10, with a hydride reagent as a reducing agent in the presence of oxygen, to a compound of general formula (II) Ar-Hn (II), where Ar and n have the same meanings as above and H is hydrogen, characterized by the use of diisobutylaluminum hydride, diisobutylaluminium hydride/ZnCl2, Al-isopropylat, sodium-bis-(2-methoxy-ethoxy)aluminiumhydride, potassium-tri-sec-butylborohydride, lithium-tri-sec-butylborohydride, potassium trisiamylborohydride, lithium trisiamylborohydride, Li-tri-t-butoxy-AlH, Li-tri-ethoxy-AlH, 9-boroabicyclo(3.3.1)nonan, lithium triethylborohydride, AlH3.AlCl2H or a combination of at least two of the reducing agents mentioned above. The reducing reaction is carried out in the presence of a solvent and a dried mixture of oxygen and an inert gas is blown or sucked through the reaction mixture.
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