| 发明名称 |
Process for preparation of pyrazolo[4,3-d]pyrimidin-7-ones and intermediates thereof |
| 摘要 |
A process is provided for the preparation of a compound of formulae (IA) (sidenafil) and (IB)comprising reacting a compound of formula (IIA) and (IIB) respectively in the presence of -OR, wherein R in the case of formation of compound (IA) is CH2CH3 and R in the case of formation of compound (IB) is CH2CH2CH3, where X is a leaving group: |
| 申请公布号 |
US6207829(B1) |
申请公布日期 |
2001.03.27 |
| 申请号 |
US19990415440 |
申请日期 |
1999.10.08 |
| 申请人 |
PFIZER INC. |
发明人 |
DUNN PETER JAMES;LEVETT PHILIP CHARLES |
| 分类号 |
C07D295/22;A61K31/519;A61P15/10;C07D231/40;C07D231/54;C07D295/26;C07D401/02;C07D401/06;C07D487/00;C07D487/04;(IPC1-7):C07D213/00;C07D241/00;C07D403/00;C07D471/00 |
主分类号 |
C07D295/22 |
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