| 摘要 |
The invention relates to a new anti-tumoral therapy agent based on liposome-encapsulated cytostatic agents and/or the metabolites thereof. The invention can be used in the pharmaceutical industry and in medicine. The aim of the invention is to build up drug targeting to combat cancer through suitable carrier systems. The invention is characterized by the fact that it clearly increases the concentration of cytostatic agents and residence time in tumors. At the same time, toxic side-effects on the remaining organs are reduced. The inventive agent contains PEG, immuno or immuno/PEG liposome-encapsulated cytostatic agents and/or the metabolites thereof, degradable starch particles and/or gelatin and/or nanoparticles, contrast agents containing iodine, gadolinium or magnetite. A preferred agent is characterized by the cytostatic agent Carboplatinum, encapsulated in SUV-PEG, starch particle Spherex or Gelfoam and the contrast agent Gadolinium-DTPA.
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