CACNA1G POLYNUCLEOTIDE, POLYPEPTIDE AND METHODS OF USE THEREFOR

摘要

A novel T-type calcium channel (CACNA1G) is provided, as are polynucleotides encoding the same. CACNA1G has been implicated in cellular proliferative disorders. More specifically, it has been observed that the methylation stat e of specific regions within CpG islands associated with the CACNA1G gene correlates with a number of cancerous phenotypes involving a variety of tiss ue and cell types. Also provided are methods for detecting cellular proliferati ve disorders by determining the methylation state of genes or regulatory region s associated therewith, including CACNA1G, as well as kits containing reagents for performing invention methods.