| 摘要 |
A process of preparing a boronic acid having the general formula, (OH)2B-Ar-B(OH)2, wherein Ar is a substituted or non-substituted divalent aromatic radical, the process comprising the steps of: (a) providing an organometallic compound, M-Ar-M, wherein each M is independently a monovalent metal radical; (b) converting the compound provided in step (a) to Z-Ar-Z, wherein each Z is independently a trialkyl silyl radical; (c) reacting the compound formed in step (b) with BX3 to form the intermediate [X2B-Ar-BX2], wherein each X is independently a halogen radical; and (d) hydrolysing the intermediate obtained in step (c) so as to form the boronic acid.
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