发明名称 POWDERY INHALING PREPARATION AND ITS PRODUCTION
摘要 PROBLEM TO BE SOLVED: To obtain a powdery inhaling preparation having a good re-dispersing property while keeping a high medicine-discharging property, and an excellent powder fluidity and improving the medicine-attainability to the region of a disease. SOLUTION: This powdery inhaling preparation used by a dry powder inhaling tool contains (a) a fine particle mixture obtained by a method of mixing an azulene derivative having a thromboxane-antagonizing activity with an additive and then mixing and crushing it to a fine particle state and (b) a carrier particles of a saccharide, a sugar alcohol, an amino acid or the like. The method for production is simple, and in the case of inhaling by using a dry powder- inhaling tool, the discharging property from the inhaling tool is not damaged and it is possible to achieve a high lung attainability.
申请公布号 JP2001072586(A) 申请公布日期 2001.03.21
申请号 JP19990251120 申请日期 1999.09.06
申请人 NIKKEN CHEM CO LTD;KOTOBUKI SEIYAKU KK 发明人 OKUMURA MUTSUO;HAKAMATA HIDEKI;SEKI HIROSHI
分类号 A61K47/10;A61K9/14;A61K31/18;A61K47/16;A61K47/26;A61P11/06;(IPC1-7):A61K31/18 主分类号 A61K47/10
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