摘要 |
A method of injecting a DNA-based injectable into a human, using a needle-free injection system, is provided. The method includes the steps of first pressuring an injectate within an ampule having a nozzle orifice. A peak pressure of approximately 3900-4300 psi adjacent the nozzle, is reached. Then the pressure is immediately reduced to approximately 1200-2100 psi while the injection is continuing. This distributes the DNA-based injectable throughout the muscle tissue and traumatizes the tissue. The pressure is cut-off, normally within 10 ms, to terminate the injection process. |