发明名称 |
BICARBONATE-BASED SOLUTION IN TWO PARTS FOR PERITONEAL DIALYSIS OR SUBSTITUTION IN CONTINUOUS RENAL REPLACEMENT THERAPY |
摘要 |
The present invention provides devices and methods for stabilizing bicarbona te- based solutions for peritoneal dialysis or hemofiltration. The bicarbonate- based solutions of the present invention are formulated and stored in at lea st two parts - an alkaline bicarbonate concentrate and an acidic concentrate. T he alkaline bicarbonate concentrate is adjusted to have a pH of about 8.6 to 10.0. The acidic concentrate is adjusted to have a stable, acidic pH ranging from about 1.0 to 3.0. Upon mixing, although some variation in the pH of the mixed bicarbonate solution exists, the inventors have discovered that with t he appropriate selection of the parameters of the concentrates, the pH of the mixed solution is always within an acceptable physiological range.
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申请公布号 |
CA2352561(A1) |
申请公布日期 |
2001.03.15 |
申请号 |
CA20002352561 |
申请日期 |
2000.07.27 |
申请人 |
BAXTER INTERNATIONAL INC. |
发明人 |
PELUSO, FRANCESCO;MARTIS, LEO;BALTEAU, PATRICK;FAICT, DIRK;DUPONCHELLE, ANNICK;HARTMAN, JEAN-PIERRE |
分类号 |
A61J1/10;A61K33/14;A61M1/16;A61M1/28;(IPC1-7):A61K33/10;A61P13/12 |
主分类号 |
A61J1/10 |
代理机构 |
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