| 发明名称 |
HETEROCYCLIC CONTAINING BIPHENYL aP2 INHIBITORS AND METHOD |
| 摘要 |
aP2 inhibiting compounds are provided having formula (I) wherein R<1>, R<2>, R<3>, R<4>, X-Z and (a) are as described herein. A method is also provided for treating diabetes and related diseases, especially Type II diabetes, employing such aP2 inhibitor or a combination of such aP2 inhibitor and another antidiabetic agent such as metformin, glyburide, troglitazone and/or insulin.
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| 申请公布号 |
WO0059506(A8) |
申请公布日期 |
2001.03.08 |
| 申请号 |
WO2000US07417 |
申请日期 |
2000.03.20 |
| 申请人 |
BRISTOL-MYERS SQUIBB CO. |
发明人 |
ROBL, JEFFREY, A.;SULSKY, RICHARD, B.;MAGNIN, DAVID, R. |
| 分类号 |
A61K31/341;A61K31/357;A61K31/381;A61K31/41;A61K31/415;A61K31/4164;A61K31/4178;A61K31/4196;A61K31/421;A61K31/422;A61K31/444;A61K45/00;A61K45/06;A61P1/00;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P11/00;A61P19/02;A61P37/06;A61P43/00;C07D207/32;C07D207/323;C07D207/333;C07D207/44;C07D207/444;C07D207/452;C07D231/12;C07D231/22;C07D233/54;C07D233/56;C07D233/60;C07D233/64;C07D233/68;C07D249/12;C07D263/32;C07D307/12;C07D307/42;C07D317/22;C07D333/20;C07D403/10;C07D403/12;C07D405/10;C07D405/12;C07D413/10;C07D413/12;C07D413/14;(IPC1-7):A61K31/41;A61K31/416;A61K31/417;A61K31/419;A61K31/424;C07D257/10;C07D263/30;C07D263/34;C07D403/00 |
主分类号 |
A61K31/341 |
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