| 发明名称 |
INDUCTION OF PROGRAMMED CELL DEATH BY N5 GENE |
| 摘要 |
The present invention concerns methods and compositions for treating cancer in a subject. These methods and compositions utilize the activities associated with the N5 gene product, p84N5. p84N5 contains a functional death domain, c an interact with the retinoblastoma gene product and is normally localized to t he nucleus of cells. Increasing the activity level of p84N5 in cancer cells is beneficial for the treatment of cancer.
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| 申请公布号 |
CA2382952(A1) |
申请公布日期 |
2001.03.08 |
| 申请号 |
CA20002382952 |
申请日期 |
2000.08.31 |
| 申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
GOODRICH, DAVID;DOOSTZADEH, JALEH;YIN, SHENMIN |
| 分类号 |
A61K38/00;A61K48/00;C07K14/47;(IPC1-7):A61K39/245;C12N5/10;C12N15/12;A61K39/21;A61K39/235;C12N15/86;C12N15/861;C12N15/867;C12N15/869 |
主分类号 |
A61K38/00 |
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