| 发明名称 |
Monoclonal antibody specific to polypeptide which induces interferon-gamma production |
| 摘要 |
A monoclonal antibody which is specific to a polypeptide having a molecular weight of 18, 500 3,000 daltons on SDS-PAGE and a pI of 4.9 1.0 on chromatofocusing. The monoclonal antibody is obtainable from hybridomas and can be used for the purification and detection of the polypeptide. The polypeptide strongly induces the IFN-gamma production by immunocompetent cells with only a small amount, and does not cause serious side effects even when administered to human in a relatively-high dose
|
| 申请公布号 |
US6197297(B1) |
申请公布日期 |
2001.03.06 |
| 申请号 |
US19950558818 |
申请日期 |
1995.11.15 |
| 申请人 |
KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO |
发明人 |
KUNIKATA TOSHIO;TANIGUCHI MUTSUKO;KOHNO KEIZO;KURIMOTO MASASHI |
| 分类号 |
G01N33/53;A61K38/00;A61K38/19;A61K38/21;A61K39/395;C07K1/16;C07K1/18;C07K1/22;C07K1/26;C07K1/30;C07K1/34;C07K14/52;C07K14/54;C07K14/555;C07K14/57;C07K16/00;C07K16/24;C12N5/10;C12N15/02;C12N15/07;C12P21/08;C12R1/91;G01N33/577;(IPC1-7):A61K39/395;C07K16/34 |
主分类号 |
G01N33/53 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
