| 发明名称 |
NOUVELLE METALLOPROTEASE MATRICIELLE MMP-24 HOMOLOGUE AUX STROMELYSINES |
| 摘要 |
The invention concerns a novel MMP-27 transmembrane matrix metalloproteinase which is expressed in tumour cells. The invention concerns a method for screening compounds capable of affecting the activity of MMP-27, and the use of said compounds for making a medicine for the treatment of cancer, in particular for preventing and/or inhibiting the formation of metastases, vascularization of tumours and for treating inflammatory diseases.
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| 申请公布号 |
FR2797890(A1) |
申请公布日期 |
2001.03.02 |
| 申请号 |
FR19990010937 |
申请日期 |
1999.08.31 |
| 申请人 |
PIERRE FABRE MEDICAMENT |
发明人 |
BENOIT DE COIGNAC AMELIE;ELSON GREG;GAUCHAT JEAN FRANCOIS |
| 分类号 |
A61K48/00;A61P9/00;A61P29/00;A61P35/00;C12N9/64;C12N15/57;C12Q1/37;(IPC1-7):C12N15/57;C12N15/63;C07K16/40;C12Q1/68;G01N33/53 |
主分类号 |
A61K48/00 |
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