COMPOSITION FOR PREVENTING AND TREATING CARDIOVASCULAR DISEASES COMPRISING SAGASSUM SERRATIFOLIUM EXTRACT

摘要

The present invention relates to a pharmaceutical composition for preventing or treating cardiovascular diseases, comprising a Sagassum serratifolium extract as an active ingredient. More specifically, the Sagassum serratifolium extract and a compound separated from the extract of the present invention do not generate the cytotoxicity, and have stability. The Sagassum serratifolium extract and the compound separated from the extract can inhibit the expression of the protein and the gene of inflammation-associated factors, and can activate an anti-inflammation activating factor. In addition, the Sagassum serratifolium extract and the compound separated from the extract have effects in being used as an ingredient of a functional food and drugs for preventing, alleviating, and treating the damaged blood vessel by inhibiting the conjugation of a monocyte with an endothelial cell through the inhibition of factors such as ICAM-1 and VCAM-1.