发明名称 Dendritic polypeptides
摘要 A dendritic compound comprises two dendrons, each comprising dendritically linked amino acid units, preferably lysine units, joined to a focal group. One of the dendrons includes terminal branches including anchor groups constituted by hydrophobic units and the second dendron has terminal branches which are linked or may be linked to active ligands or sugar moieties. Methods for synthesising the dendritic compounds using solid phase peptide synthetic techniques including lipidic amino acid reagents is described. The compounds serve as a basis for multiple antigenic peptides or drug delivery systems.
申请公布号 US6194543(B1) 申请公布日期 2001.02.27
申请号 US19980096411 申请日期 1998.06.11
申请人 THE SCHOOL OF PHARMACY UNIVERSITY 发明人 FLORENCE ALEXANDER T.;SAKTHIVEL THIAGARAJAN;WILDERSPIN ANDREW F.;TOTH ISTVAN
分类号 A61K9/00;A61K38/00;A61K47/48;C07K1/04;C07K1/10;C07K2/00;C07K14/00;(IPC1-7):A61K38/04 主分类号 A61K9/00
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