发明名称 |
Lipopeptides from actinoplanes sp. with pharmacological action, process for their production and the use thereof |
摘要 |
The invention relates to lipopeptides with very homologous amino-acid sequences but different fatty acid residues (lipid portion) which are synthesized by Actinoplanes sp. during fermentation and are released into the culture medium, to a process for isolating the lipopeptides from the culture medium and purifying them, to the use of the lipopeptides as pharmacologically active substances, in particular against Gram-positive bacteria, and to Actinoplanes sp. DSM 7358 for producing the abovementioned lipopeptides.
|
申请公布号 |
US6194383(B1) |
申请公布日期 |
2001.02.27 |
申请号 |
US19970811843 |
申请日期 |
1997.03.05 |
申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
HAMMANN PETER;MEIWES JOHANNES;SEIBERT GERHARD;VERTESY LáSZLO;WINK JOACHIM;MARKUS ASTRID |
分类号 |
C12P21/02;A61K38/00;A61K38/08;A61K38/12;A61P31/04;C07K;C07K1/20;C07K7/06;C07K7/60;C07K14/195;C07K14/41;C12N1/20;C12P1/06;C12P21/04;C12R1/045;(IPC1-7):A61K38/00;C07K7/64 |
主分类号 |
C12P21/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|