发明名称 |
Polyketide production and polyketide synthase libraries in E.coli and yeast |
摘要 |
Hybrid and novel polyketide synthases and polyketides are produced by use of a multiple vector system. The combinatorial possibilities offered by placing the various catalytic activities of PKS systems on separate vectors permits the construction of improved libraries of PKS and polyketides. In addition, polyketides can be produced in hosts that ordinarily do not produce polyketides by supplying, along with an expression system for the desired PKS, an expression system for holo ACP synthase. |
申请公布号 |
NZ336140(A) |
申请公布日期 |
2001.02.23 |
申请号 |
NZ19970336140 |
申请日期 |
1997.12.12 |
申请人 |
KOSAN BIOSCIENCES |
发明人 |
BARR, PHILIP J;SANTI, DANIEL V;ASHLEY, GARY W;ZIERMANN, RAINER |
分类号 |
G01N33/50;C12N1/19;C12N1/21;C12N9/00;C12N9/10;C12N9/12;C12N15/09;C12N15/52;C12N15/70;C12N15/76;C12N15/81;C12P7/26;C12P7/42;C12P19/62;C12R1/19;C12R1/865;G01N33/15 |
主分类号 |
G01N33/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|