| 发明名称 |
Spiro-indolines as Y5 receptor antagonists |
| 摘要 |
Compounds of the general structural formula Iare selective NPY Y5 receptor antagonists. The compounds and compositions of the present invention are useful in the treatment of obesity and complications associated therewith.
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| 申请公布号 |
US6191160(B1) |
申请公布日期 |
2001.02.20 |
| 申请号 |
US19990436120 |
申请日期 |
1999.11.08 |
| 申请人 |
MERCK & CO., INC.;BANYU PHARMACEUTICAL CO., LTD. |
发明人 |
GAO YING-DUO;MACNEIL DOUGLAS J.;YANG LIHU;MORIN NANCY R.;FUKAMI TAKEHIRO;KANATANI AKIO;FUKURODA TAKAHIRO;ISHII YASUYUKI;IHARA MASAKI |
| 分类号 |
A61K31/403;A61K31/404;A61K31/4155;A61K31/4178;A61K31/4375;A61K31/438;A61K31/4427;A61K31/4439;A61K31/444;A61K31/4709;A61K31/497;A61K31/498;A61K31/501;A61K31/506;A61P3/04;A61P3/06;A61P3/10;A61P7/04;A61P9/04;A61P13/02;A61P15/00;A61P19/02;A61P25/04;A61P25/06;A61P25/08;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P37/02;C07D209/96;C07D221/20;C07D401/12;C07D403/12;C07D471/04;C07D471/10;C07D471/20;C07D487/10;C07D487/20;C07D519/00;(IPC1-7):A61K31/495;A61K31/40;C07D239/02;C07D209/54;C07D277/60 |
主分类号 |
A61K31/403 |
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