发明名称 IMIDAZOLE ANTIPROLIFERATIVE AGENTS
摘要 Compounds of formula (I) or a pharmaceutically acceptable salt or prodrug thereof, wherein R<1> is selected from the group consisting of hydrogen, methyl, ethyl, propyl, and isolpropyl; and one of R<2> or R<3> is 3,4,5-trimethoyxphenyl, and the other is phenyl substituted with one, two, or three substitutents independently selected from the group consisting of alkoxy, halo, and -NR<4>R<5>, wherein R<4> and R<5> are independently selected from the group consisting of hydrogen and alkyl, inhibit celluar proliferation. Processes for the preparation of the compounds, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds are disclosed.
申请公布号 WO0109103(A2) 申请公布日期 2001.02.08
申请号 WO2000US20053 申请日期 2000.07.21
申请人 ABBOTT LABORATORIES 发明人 WANG, LE;LI, QUN;SHAM, HING, L.;WOODS, KEITH, W.
分类号 C07D233/64;A61K31/4164;A61P35/00;A61P43/00;C07D233/54;(IPC1-7):C07D233/00 主分类号 C07D233/64
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