发明名称 Transcobalamin mediated transport of vitamins B12 in intrinsic factor or receptor deficient patient
摘要 A method for oral treatment of patients using different types of drugs that are not usually transported to circulation, if administered orally, is disclosed. Because the TC II-Cbl complex is stable to acid and proteolytic enzymes both outside and inside the intestinal absorptive cells, the method consists of oral administration of a drug bound to TC II-Cbl complex. In addition, the method can also be used for delivering Cbl to a large number of patients who do not absorb Cbl due to a variety of causes such as surgery of their stomach (ulcers) or of their terminal ileum (Crohn's disease).
申请公布号 US6183723(B1) 申请公布日期 2001.02.06
申请号 US19980009995 申请日期 1998.01.21
申请人 MCW RESEARCH FOUNDATION 发明人 SEETHARAM BELLUR;BOSE SANTANU
分类号 A61K38/00;A61K49/00;(IPC1-7):A61K49/00 主分类号 A61K38/00
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