发明名称 Hematopoietic arabinogalactan composition
摘要 Purified arabinogalactan compositions isolated from <i>Astragalus membranaceus</i>, especially from the roots of <i>Astragalus membranaceus</i> , and arabinogalactan protein compositions having a weight average molecular weight of at least 100 kiloDaltons isolated from these purified arabinogalactan compositions, are capable of reconstitution into aqueous intravenously injectable formulations; and are useful for stimulating hematopoiesis; inducing the proliferation or maturation of megakaryocytes, stimulating the production of IL-1 beta , IL-6, TNF- alpha , IFN- gamma , GM-CSF, or G-CSF, stimulating the production or action of neutrophils, treating neutropenia, anemia, or thrombocytopenia, accelerating recovery from exposure (e.g. accidental or non-therapeutic exposure, as well as therapeutic exposure) to cytotoxic agents or radiation, treating cachexia, emesis, or drug withdrawal symptoms, or modifying biological responses or protecting hepatic cells in hepatitis B, in a mammal when intravenously administered to the mammal.
申请公布号 AU6203600(A) 申请公布日期 2001.01.31
申请号 AU20000062036 申请日期 2000.06.30
申请人 PHARMAGENESIS, INC. 发明人 JINHUA AN;KAREN S. LEU;EDWIN S. LENNOX;JOHN H. MUSSER
分类号 A61K36/48;C08B37/00 主分类号 A61K36/48
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