发明名称 |
21-(2-OXO-TETRAHYDROFURAN)-THIO PREGNANE DERIVATIVES, A PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
<p>PCT No. PCT/GB96/03153 Sec. 371 Date Jun. 24, 1998 Sec. 102(e) Date Jun. 24, 1998 PCT Filed Dec. 19, 1996 PCT Pub. No. WO97/24367 PCT Pub. Date Jul. 10, 1997Compounds of the pregnane series are described having general formula (I) or their solvates in which R1 individually represents -OC(=O)C1-6 alkyl; R2 individually represents hydrogen, methyl (which may be in the alpha or beta configuration) or methylene; or R1 and R2 together represent formula (a) where R5 and R6 are the same or different and each represents hydrogen or C1-6 alkyl; R3 and R4 are the same or different and each represents hydrogen or halogen; and +Z represents a single or a double bond. Compounds of formula (I) and their solvates are useful as anti-inflammatory or anti-allergic agents.</p> |
申请公布号 |
GR3034563(T3) |
申请公布日期 |
2001.01.31 |
申请号 |
GR20000402253T |
申请日期 |
2000.10.04 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
BIGGADIKE, KEITH;FARRELL, ROSANNE, MARY |
分类号 |
A61K31/565;A61K31/00;A61P29/00;C07J31/00;C07J71/00;(IPC1-7):C07J31/00 |
主分类号 |
A61K31/565 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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