LCAT RECOMBINANT CELL LINE COMPOSITIONS AND METHODS

摘要

Disclosed are compositions, kits and devices comprising engineered cells that secrete therapeutically effective levels of lecithin-cholesterol acyltransferase (LCAT). Methods of using such cells in various diagnostic and therapeutic embodiments are also provided, including effective treatment of LCAT deficiencies, such as atherosclerosis, using surprisingly low cell doses and prognostic assay methods.