发明名称 NEW PROCESS FOR THE PREPARATION OF N-(1,1-DIMETHYLETHYL)-4-[[5'-ETHOXY-4-CIS-[2-(4-MORFOLINO)ETHOXY]-2'-OXOSPIRO[CYCLOHEXAN-1,3'-[H]INDOL]-1'(2'H)-YL]-SULFONYL]-3-METHOXYBENZAMIDEAND ITS SALTS
摘要 The invention relates to a process for the preparation of a compound of formula (I) and the salts thereof by reacting the compound of formula (II) with the compound of formula (III), which comprises carrying out the reactio n in dimethyl sulfoxide, at a temperature between 10 ~C and 40 ~C, preferably at room temperature and transforming the resulting base of formula (I), if desired, into its salt by a method known per se.
申请公布号 CA2378087(A1) 申请公布日期 2001.01.25
申请号 CA20002378087 申请日期 2000.07.13
申请人 SANOFI-SYNTHELABO 发明人 HERMECZ, ISTVAN;SAROSI, PETER;HALASZ, JUDIT;CSIKOS, EVA;SANTANE CSUTOR, ANDREA;NAGY, LAJOS;HEJA, GERGELY;SZOMOR, TIBORNE;SZVOBODA, GYORGYNE;MAJLATH, CSILLA;SIMON, KALMAN;GONCZI, CSABA;EROSNE TAKACSY, TUNDE POSA
分类号 A61K31/5377;A61P5/12;C07B61/00;C07D209/96;(IPC1-7):C07D209/96 主分类号 A61K31/5377
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