发明名称 |
Fima PILUS-BASED VACCINES |
摘要 |
Novel polypeptides formed from amino acid sequences corresponding to exposed domains on the surface of FimA, a protein making up a portion of type 1 pili of bacteria, such as <i>E. coli</i>, are disclosed. Also disclosed are compositions containing these novel polypeptides for use as vaccines and for generating specific antibodies for use in treatment and/or prevention of diseases, such as urinary tract infections, caused by bacteria of the family <i>enterobacteriaceae</i>.
|
申请公布号 |
WO0105827(A1) |
申请公布日期 |
2001.01.25 |
申请号 |
WO2000US19277 |
申请日期 |
2000.07.14 |
申请人 |
MEDIMMUNE, INC. |
发明人 |
HULTGREN, SCOTT, J.;LANGERMANN, SOLOMON |
分类号 |
C12N15/09;A61K39/00;A61K39/108;A61K39/395;A61P13/02;A61P13/10;A61P13/12;A61P31/04;C07K14/245;C07K16/12;C12N15/31;C12P21/08;(IPC1-7):C07K14/245 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|