| 发明名称 |
OXATHIEPINO[6,5-B]DIHYDROPYRIDINES, AND RELATED COMPOSITIONSAND METHODS |
| 摘要 |
This invention provides novel oxathiepino[6,5-b]dihydropyridines. These compounds are useful as calcium channel antagonists with cardiovascular, antiasthmatic and antibronchoconstriction activity. Thus, this invention als o provides pharmaceutical compositions, as well as methods, for preventing and treating disorders such as hypersensitivity, allergy, asthma, bronchospasm, dysmenorrhea, esophageal spasm, glaucoma, premature labor, urinary tract disorders, gastrointestinal motility disorders and cardiovascular disorders.
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| 申请公布号 |
CA2379199(A1) |
申请公布日期 |
2001.01.18 |
| 申请号 |
CA20002379199 |
申请日期 |
2000.06.23 |
| 申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
DODD, JOHN H.;HENRY, JAMES R.;RUPERT, KENNETH C.;BULLINGTON, JAMES L.;HALL, DANIEL A. |
| 分类号 |
A61K31/4365;A61P1/06;A61P1/14;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P11/08;A61P13/04;A61P15/00;A61P15/06;A61P25/02;A61P27/06;A61P37/08;C07D221/00;C07D327/00;C07D495/04;C07D497/04;(IPC1-7):C07D497/04;A61M11/00;A61K31/436 |
主分类号 |
A61K31/4365 |
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