AEROSOLIZED ANTI-INFECTIVES, ANTI-INFLAMMATORIES, AND DECONGESTANTS FOR THE TREATMENT OF SINUSITIS

摘要

Pharmaceutical compositions are described that comprise one or more active ingredients selected from the group consisting of anti-infective, anti-inflammatory and anti-mucolytic agents, and particularly to compositions formulated as a solution in a unit dose for aerosol administration to treat chronic sinusitis. The figure discloses the preferred equipment for aerosolized delivery of pharmaceutical solutions. This nebulizer, manufactured by Pari Respiratory Equipment, Inc., for the inventors, produces the desired particle size for affective administration of the solutions in this invention to the sinuses. To use this nebulizer preferably medication is placed in the nebulizer at (A). The nebulizer is then connected to compressor or other source at (B) with tubing supplied. When the airflow is turned on, the patient places the nose piece (C) under their nostrils and breathes normally until the medication solution in the nebulizer begins to sputter and no mist comes out at (C).