| 发明名称 |
Methods and products for manipulating uncoupling protein expression |
| 摘要 |
The invention is based in part on the discovery that uncoupling proteins (UCPs) are expressed in the plasma membrane of rapidly dividing cells but not of growth arrested, chemotherapy resistant cells. It has also been found according to the invention that UCP is expressed in the lysosomal membrane under certain metabolic conditions. Thus the invention is methods, products, screening assays and kits relating to the manipulation of UCP expression within cellular and intracellular membranes. |
| 申请公布号 |
AU5760000(A) |
申请公布日期 |
2001.01.09 |
| 申请号 |
AU20000057600 |
申请日期 |
2000.06.22 |
| 申请人 |
UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE |
发明人 |
MARTHA K. NEWELL |
| 分类号 |
G01N33/48;A61K9/10;A61K9/127;A61K31/19;A61K31/7052;A61K31/7068;A61K31/7072;A61K31/7076;A61K31/708;A61K38/00;A61K39/00;A61K39/002;A61K39/02;A61K39/12;A61K39/395;A61K45/00;A61K47/42;A61K47/48;A61K48/00;A61P3/10;A61P17/00;A61P29/00;A61P31/04;A61P31/12;A61P33/00;A61P35/00;A61P35/02;A61P37/02;A61P43/00;C07K14/47;C07K16/18;C12N5/06;C12N15/09;C12Q1/02;C12Q1/68;G01N33/50 |
主分类号 |
G01N33/48 |
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