Compositions and methods for the prevention, treatment and detection of tuberculosis and other diseases

摘要

Compositions and methods of their use for the prevention and treatment of M. tuberculosis, M. pneunomia, and other diseases related to anaerobic microorganisms are presented. These new agents inhibit their target microorganisms and represent a new class of medically active substances. Preferred embodiments indirectly or directly target the enzyme carbon monoxi de dehydrogenase, which generally is found in these organisms.