发明名称 |
Method of targeting conjugate molecules to mitochondria |
摘要 |
The present invention relates to genetic mutations in mitochondrial cytochrome c oxidase genes that segregate with Alzheimer's disease (AD). The invention provides methods for detecting such mutations, as a diagnostic for Alzheimer's Disease, either before or after the onset of clinical symptoms. The invention further provides treatment of cytochrome c oxidase dysfunction.
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申请公布号 |
US6171859(B1) |
申请公布日期 |
2001.01.09 |
申请号 |
US19950413740 |
申请日期 |
1995.03.30 |
申请人 |
MITOKOR |
发明人 |
HERRNSTADT CORINNA;PARKER WILLIAM DAVIS;KIELY JOHN S;DAVIS ROBERT E;GHOSH SOUMITRA S |
分类号 |
A61K38/00;C07D219/08;C07K14/47;C12N9/02;C12P21/04;C12Q1/68;(IPC1-7):C12N15/64 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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