| 摘要 |
<p>Provided are methods for selecting peptide immunogens for a target protein from a first species which has an amino acid sequence different from the analogous protein from a second species. The method comprises selecting peptide fragments from the target protein which are hydrophilic and which vary in sequence from the analogous protein by at least one amino acid. Antibodies made using the selected immunogens conjugated to a carrier molecule are also provided. Antibodies made by this method to rabbit tissue factor which do not cross-react with human tissue factor are also provided.</p> |
