发明名称 |
NEOVASCULARIZATION INHIBITOR |
摘要 |
The present invention relates to a neovascularization inhibitor comprising as an active ingredient N-(3,4-dimethoxycinnamoyl) anthranilic acid represented by the formula: <CHEM> or a pharmaceutically acceptable salt thereof, which has inhibitory effects on proliferation and chemotaxis of human microvascular endothelial cells and tube formation of human microvascular endothelial cells, and therefore, is useful as an agent for the prevention and treatment of diseases associated with neovascularization such as diabetic retinopathy, senile discoid macular degeneration, neovascular glaucoma and rheumatic arthritis. |
申请公布号 |
EP0894496(A4) |
申请公布日期 |
2001.01.03 |
申请号 |
EP19970902651 |
申请日期 |
1997.02.12 |
申请人 |
KISSEI PHARMACEUTICAL CO., LTD. |
发明人 |
ISAJI, MASAYUKI;MIYATA, HIROSHI;AJISAWA, YUKIYOSHI |
分类号 |
A61K31/196 |
主分类号 |
A61K31/196 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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