发明名称 Process for the preparation of fluorinated benzoic acids
摘要 A process for the preparation of 2-chloro-4,5-difluorobenzoic acid and 2,4,5-trifluorobenzoic acid as well as acid fluorides thereof, comprising reacting a benzoyl chloride having the formula (V), wherein X' is chloro or fluoro, one of Y and Z is chloro and the other of Y and Z is nitro, with an appropriate fluoride, subject to the proviso that the benzoyl chloride, wherein Z is chloro, is used for the preparation of 2-chloro-4,5-difluorobenzoic acid and the acid fluoride thereof. <CHEM>
申请公布号 EP0781757(B1) 申请公布日期 2001.01.03
申请号 EP19970101115 申请日期 1992.10.30
申请人 ABBOTT LABORATORIES 发明人 WANG, XIU C.;KALARITIS, P.;CHANG, MICHELLE L.
分类号 C07C51/04;C07C51/363;C07C63/10;C07C63/70;C07C201/12;C07C205/12;C07C205/45;C07C205/56;C07C205/58;C07C253/30;C07C255/35;C07C255/41;(IPC1-7):C07C63/70;C07B39/00 主分类号 C07C51/04
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