发明名称 |
NOVEL PHYSIOLOGICALLY ACTIVE PEPTIDES AND UTILIZATION THEREOF |
摘要 |
<p>The present invention relates to a peptide comprising an amino acid sequence identical to or substantially identical to an amino acid sequence represented by SEQ ID NO: 35 and having an ability of binding to a receptor protein comprising an amino acid sequence identical to or substantially identical to an amino acid sequence represented by SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 3, or a precursor thereof, its amide or ester, or a salt thereof. An inventive peptide-encoding DNA or equivalent can be employed in (1) a development of a receptor binding assay system using an expression system of a recombinant receptor protein and a screening for a pharmaceutical candidate compound, and (2) a development of a pharmaceutical having a reduced side effect such as memory function improving agent, an appetite improving agent, an uterine, renal, prostatic, testicular or skeletal muscle function regulating agent.</p> |
申请公布号 |
EP1065214(A1) |
申请公布日期 |
2001.01.03 |
申请号 |
EP19990910677 |
申请日期 |
1999.03.24 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
OHTAKI, TETSUYA;MATSUI, HIDEKI;ISHIBASHI, YOSHIHIRO;OGI, KAZUHIRO;KITADA, CHIEKO |
分类号 |
A61K38/00;C07K14/47;C07K14/705;C07K14/72;C07K16/18;C12N15/12;(IPC1-7):C07K14/47;A61K38/17;C12P21/02 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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