摘要 |
A sensor for detecting analytes of interest is described. Analyte presence or concentration is determined through measurement of changes in induced electromotive force, current or other electrical property in a sensor strip during analyte exposure to the sensor. According to one class of embodiments, the present device immobilizes natural or synthetic macromolecules sufficiently close to an electrically-conductive base member to insure that interaction of analyte with the macromolecules will lead to altered <i>de novo</i> electrical signals in the sensor strip of base member and macromolecules. Performance of the sensor is enhanced by the use of a resistance-modifying element in a circuit that includes the sensor strip, and by an adhesive agent disposed between the base member and at least one electrical lead of a detection unit. |