发明名称 MACROLIDE TETRAHYDROPYRANE DERIVATIVES, PROCESS TO PREPARE THEM AND PHARMACEUTICAL COMPNS.CONTG. THE SAID COMPDS.
摘要 The invention concerns the compounds of formula I <CHEM> wherein the substituents have various significances, in free form and, where such forms exist, in salt form. They can be prepared by various processes, e.g. by irradiation; oxidation; elimination; reduction; conversion by e.g. halogenation or acylation; deprotection of protected hydroxy groups; protection of free hydroxy groups; and separation of stereoisomeric mixtures into individual isomers. They are indicated for use as pharmaceuticals, especially as antiinflammatory, and as antiproliferative and antiinflammatory agents.
申请公布号 HU218919(B) 申请公布日期 2000.12.28
申请号 HU19940001582 申请日期 1994.05.25
申请人 Novartis AG. 发明人 BULUSU, MURTY A.R.C.
分类号 A61K31/40;A61K9/00;A61K31/352;A61K31/357;A61K31/407;A61K31/435;A61K31/436;A61K31/445;A61P29/00;A61P35/00;A61P37/06;C07D498/12;C07D498/16;C07D498/18;C07H19/01 主分类号 A61K31/40
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