发明名称 Herpes simplex virus expressing foreign genes and method for treating cancers therewith
摘要 An anti-cancer pharmaceutical composition includes a herpes simplex virus (HSV) vector into which a nucleic acid sequence encoding for an anti-cancer agent selected from interleukin-12, GM-CSF, and CD has been inserted. A method of treatment of a patient suffering from cancer includes administering to the patient the anti-tumor pharmaceutical composition including an HSV vector having a nucleic acid sequence encoding for an anti-cancer agent selected from interleukin-12, GM-CSF, and CD inserted therein.
申请公布号 AU6120600(A) 申请公布日期 2000.12.28
申请号 AU20000061206 申请日期 2000.06.08
申请人 UAB RESEARCH FOUNDATION 发明人 RICHARD J. WHITLEY;JAMES MACDOWELL MARKERT;GEORGE YANCEY GILLESPIE;JACQUELINE NESS PARKER
分类号 C12N15/09;A61K35/76;A61K38/00;A61K38/19;A61K38/20;A61K38/43;A61K38/50;A61K48/00;A61P35/00;C12N9/78;C12N15/869 主分类号 C12N15/09
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