A pharmaceutical composition is provided containing an admixture of phenytoin sodium and an erodible matrix which extends the release of the phenytoin sodium over about a two hour period. The erodible matrix comprises binder(s) and diluent(s) which control the release of drug from the pharmaceutical composition. The erodible matrix can further comprise an alkaline pH modifier.
申请公布号
WO0050014(A3)
申请公布日期
2000.12.21
申请号
WO2000US04285
申请日期
2000.02.22
申请人
MYLAN PHARMACEUTICALS, INC.
发明人
ADDICKS, WILLIAM, J.;DUDA, JOSEPH, P.;SNIDER, DANIEL, A.;BENSON, KERRY, R.